[Fis] Emotion & The Immune System

[Katherine Peil]

Dear FIS community,

Sorry for the silence. Medical crises have transformed to grieving processes and Stu and I will be in transit until next week.

But in the meantime, I’d love to hear some of your thoughts on the role of information in the immune system, particularly the innate immune system. (Link and pdf attached below).
My take on the self-regulatory function emotion suggests that the dual  “purposes” of self-preservation and adaptive self-development (both mediated by Negative ~ Positive categories of emotions) are rooted in ancient information signaling and memory systems.
So a few more questions to ponder:
How deep does molecular sensing and actuation go? Is any subjectivity involved in information processing? At what point is it purely mechanical?
And once again, where does the semantic value enter the picture? Food vs poison? (Yum and Yuk, as Stu would say)? Not-self pathogens? Too hot, too cold?
Why are certain realities “painful”? And what does that tell us about “reality” proper?
With humility and fond affections,
Kate
PS Thank you all for the previous comments. (Karl, thanks for your detailed offering on The Tao of Numbers. I hope we can find that common language.)

https://urldefense.com/v3/__https://www.nature.com/articles/d41586-024-01274-3?utm_source=Live*Audience&utm_campaign=a5697c9afa-nature-briefing-daily-20240508&utm_medium=email&utm_term=0_b27a691814-a5697c9afa-50138668__;Kw!!D9dNQwwGXtA!XViuzu8wz8b4rAglGifwRZ9PYnmrRpTHT_ADAM5P__6NfBruRlDtAGxTguBX7RttK0svYyf7YoqMkWwdFQ$ 
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://listas.unizar.es/pipermail/fis/attachments/20240509/1c3d3e51/attachment-0001.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: Immune  System & Aging.pdf
Type: application/pdf
Size: 466605 bytes
Desc: Immune  System & Aging.pdf
URL: <http://listas.unizar.es/pipermail/fis/attachments/20240509/1c3d3e51/attachment-0001.pdf>