[Fis] Fwd: NEW YEAR LECTURE--from Jerry Chandler

[Pedro C. Marijuán]

_Mssg. from Jerry Chandler_

List, Pedro, Youri,

> On Jan 19, 2022, at 12:55 PM, Pedro C. Marijuán 
> <pedroc.marijuan at gmail.com <mailto:pedroc.marijuan at gmail.com>> wrote:
>
> So, my contention is that a new filed like bio-chemistry or 
> bio-physics would be needed concerning the biological-informational 
> themes, a bio-information discipline comparable to those just 
> mentioned. According to several authors  (me included), the 
> prokaryotic cell should be considered as the fundamental, basic unit 
> of biological cognition. Thereafter, there would be different ways to 
> characterize its informational processes, particularly along the 
> "information flow" conceptualization... interested parties may go to 
> the recent contribution of Jorge Navarro and 
> mine:https://www.mdpi.com/1422-0067/22/21/11965, it is in the special 
> issue coordinated by Youri.  I also discuss that the from the 
> informational thinking one could find the ways and means to renew the 
> outdated Modern Synthesis.
>
> Otherwise, without a clearer disciplinary framework, am afraid the new 
> biology will be reduced to bioinformatics and experimental "omic" 
> disciplines. Just another (advanced, "very advanced") technology.

Pedro:  Your comments are often intriguing and these sentences are no 
exception.
I do not grasp what either your scientific or personal objectives are. 
  One consistent theme in somehow tied to expectations about “biologic 
codes” in relation to forms of communication.  Can you be more explicit 
about what sorts of meaning you are seeking to understand?
Youri has presented the FIS with an encoded diagram of one of the 
central apparati of all living organisms.  Roughly speaking, the role of 
the ribosome is well-understood although finer structuring of the 
apparatus and its dynamics will continue to be studied ad infinitum. The 
logical role of the ribosome in transducing information into alternative 
dynamic forms has been clear for more than 40 years.

  This encoded diagram is based on the epistemology of the chemical code 
of life, the physical codes of mass and electricity and the mathematical 
codes of permutation groups, space groups, number theory, and so forth.
Is it not clear that Youri’s work generates a diagram that is a logical 
constant of form?

Somehow, I suspect that the epistemic gaps between mathematics and 
physics and chemistry lie at the root of your search for biological 
codes.  Perhaps the effort is guided by a believe that the genesis of 
living dynamics, involving thousands of variables and literally hundreds 
of millions of *_unique_* biochemical reactions must necessarily be 
expressible in simplistic and other scientific, syntactical symbol 
systems?  (Hundreds of millions of reactions BECAUSE every DNA base 
occupies a logically unique sequential position and undergoes unique 
reactions during transcription and duplication.)

  Is the concern semantics or semeoius?  The syntax of Youri’s work is 
not seriously questioned, is it?  Is the problem that Youri’s work does 
not fit into alternative theories of “information” that can not be 
distorted to fit the biological codes?

Youri - Can you refer to a data source that lists the physical-chemical 
data of an E coli ribosome in terms of the parts of the whole?  (I am 
not referring x-ray data, just the chemical parameters used to compute 
the structure.). As time allows, I may do a few calculations to 
unconceal aspects of the scientific information content of a ribosome.

Cheers

Jerry





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