[Fis] Summing up: New Year Lecture--J.Torday

Tue Jan 23 09:42:07 CET 2018

-------- Mensaje reenviado --------

Asunto: 	Re: [Fis] Summing up: New Year Lecture
Fecha: 	Mon, 22 Jan 2018 07:02:42 -0800
De: 	JOHN TORDAY <jtorday at ucla.edu>
Para: 	Pedro C. Marijuan <pcmarijuan.iacs at aragon.es>

Dear FISers, I greatly appreciate Pedro's comments regarding my New Year 
Lecture. I fully agree with his comment " That life's physiology is 
based on the conjunction of a few principles: neguentropy, chemiosmosis, 
and homeostasis-homeorhesis" applies to non-living states too. I did not 
intend to make that statement exclusive, and if it sounded like that 
Pedro's clarification is important. In fact have just published a paper 
entitled "Quantum Mechanics Predicts Evolutionary Biology" which is 
predicated on the hypothesis that self-referential self-organization is 
the result of the Singularity/Big Bang, Newton's Third Law of 
Thermodynamics that every action has an equal and opposite reaction. 
That idea would apply to both evolutionary biology and to balanced 
chemical reactions alike. As for the question of the emergence of 
self-referential consciousness 'right at the beginning', I am in favor 
of that concept, as I have expressed it in a recent paper, entitled 
"From Cholesterol to Consciousness" (see attached) so I look forward to 
reading your comments about that idea as well, since it has the 
potential to fully integrate physics and biology in my humble opinion.

On Mon, Jan 22, 2018 at 4:01 AM, Pedro C. Marijuan 
<pcmarijuan.iacs at aragon.es <mailto:pcmarijuan.iacs at aragon.es>> wrote:

    Dear FISers,

    Going to the extreme, I think this year opening lecture can be
    summarized in three contentious points.

    1. That life's physiology is based on the conjunction of a few
    principles: neguentropy, chemiosmosis, and homeostasis-homeorhesis.

    2. That communication (cell signaling) is an essential factor in the
    multicellular evolution towards complexity.

    3. That epigenetic inheritance and the obligate recursion to the
    unicellular state become the basis of a new evolutionary theory.

    I disagree with point 1, as I think some nonliving states could also
    be characterized by those principles (eg, chemical
    cycles/hypercycles in marine vents, and other outcomes derived from
    "energy flows"); besides, some previous "info stuff" has to be in
    place. Then I completely agree with point 2, for signaling is not
    just another characteristic of the cell, it is "the" eukaryotic
    trait par excellence.  And I am curious on how point 3 could be
    further substantiated... In this respect I recommend the two papers
    that Bill sent to the list a few weeks ago. Do we need to postulate
    the emergence of a form of "self-referential cognition" right at the
    beginning?
    Perhaps!

    All the best--Pedro

    El 09/01/2018 a las 19:05, Bill escribió:
>     Dear Pedro and Colleagues,
>
>     I have been following the thread of comments with great interest,
>     all of  which have all been occasioned by John Torday's profound
>     insights about the nature of evolutionary development in light of
>     the importance of cell-cell signaling and molecular biology.  From
>     the comments, it is clear that there is a strong impulse to seek a
>     means of integrating the role of symbiogenesis, viruses and mobile
>     elements, multilevel selection, niche construction, genomic
>     plasticity into a common narrative with an informational
>     perspective at its foundation.
>         In the spirit of that line of discussion, I am offering two
>     links that discuss evolution as an biologic information management
>     system. Some of this work shares direct commonality with John's,
>     since he and I are frequent collaborators.
>
>     http://www.mdpi.com/2079-7737/5/2/21/htm
>     <http://www.mdpi.com/2079-7737/5/2/21/htm>
>
>     https://www.sciencedirect.com/science/article/pii/S007961071730233X
>     <https://www.sciencedirect.com/science/article/pii/S007961071730233X>
>
>     Both of these articles can be considered as complementary to
>     Pedro's very fine article, 'How prokaryotes ‘encode’ their
>     environment: Systemic tools for organizing the information flow',
>     which is in BioSystems.
>
>     I am grateful to John for inviting me to participate in the forum
>     and to Pedro for encouraging me to share these manuscripts.
>
>     Best regards,
>     Bill
>
>     William B. Miller, Jr., M.D.
>     602-463-5236 <tel:%28602%29%20463-5236>
>     wbmiller1 at cox.net <mailto:wbmiller1 at cox.net>

    -- 
    -------------------------------------------------
    Pedro C. Marijuán
    Grupo de Bioinformación / Bioinformation Group
    Instituto Aragonés de Ciencias de la Salud
    Centro de Investigación Biomédica de Aragón (CIBA)
    Avda. San Juan Bosco, 13, planta 0
    50009 Zaragoza, Spain
    Tfno.+34 976 71 3526 <tel:+34%20976%2071%2035%2026>  (& 6818)
    pcmarijuan.iacs at aragon.es <mailto:pcmarijuan.iacs at aragon.es>
    http://sites.google.com/site/pedrocmarijuan/
    <http://sites.google.com/site/pedrocmarijuan/>
    -------------------------------------------------

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