[Inageneral] RECORDATORIO Seminarios INA Primavera 2019, Segundo seminario: Elisabeth Engel 2 de mayo
Raúl Mendoza
rmendoza en unizar.es
Mar Abr 30 09:42:20 CEST 2019
Buenos días
Continuamos con el ciclo de de Seminarios INA primavera 2019, programado
para los meses de marzo a junio.
Adjunto envío cartel anunciador del segundo seminario del ciclo.
Creating microenvironments for tissue regeneration
Elisabeth Engel
Jueves, 2 de mayo, 12:00 h. Aula Edificio i+D
Abstract
*CREATING MICROENVIRONMENTS FOR TISSUE REGENERATION*
1Institute for Bioengineering of Catalonia (IBEC), The Barcelona
Institute of Science and Technology, Barcelona, Spain
2CIBER Bioengineering, Biomaterials and Nanotechnology, Spain
3Dept. Materials Science and Engineering, EEBE, Technical University of
Catalonia (UPC), Barcelona, Spain
Biomaterials have been used in regenerative medicine for years, but they
have been mainly used as scaffolds to support and guide cells or as cell
and signaling delivery carriers. Our research has focused in how the
biomaterials interact with the host environment. We have determined that
no biomaterial is inert and that all of them can affect cell behavior.
Understanding how cells interact with the biomaterials and how the
degradation products can activate metabolically the cells allows the
creation of microenvironments that can induce cell reprograming and
activation of stem and progenitor cells.
Cells are susceptible to change their phenotype and function in response
to the designed scaffolds. The selected material, topography, scaffold
structure and degradation products have to be optimized to fulfil the
requirements for each tissue (1,2). We have demonstrated that
biomaterials themselves can activate stem cells at their niche and can
either differentiate them or dedifferentiate adult cells towards a more
precursor phenotype. This is perfect for in situ tissue
engineeringapplications.
The way how we can translate and transfer the technology into products
will have a lot to do in how they are fabricated and how is the
interaction with the cells and tissues.
Saludos
Raúl
--
Raúl Mendoza Jiménez
Técnico de Apoyo a la Investigación INA
c/Mariano Esquillor s/n. (50018) zaragoza.
edificio i+d+i. Campus Rio Ebro. Universidad de Zaragoza
INA - Instituto de Nanociencia de Aragón
tel: +34 976 762865. fax: +34 976 762776
web: http://ina.unizar.es
e-mail: rmendoza en unizar.es
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