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Buenos días<br>
Continuamos con el ciclo de de Seminarios INA primavera 2019,
programado para los meses de marzo a junio.<br>
Adjunto envío cartel anunciador del segundo seminario del ciclo.<br>
<br>
Creating microenvironments for tissue regeneration<br>
Elisabeth Engel<br>
Jueves, 2 de mayo, 12:00 h. Aula Edificio i+D<br>
<br>
Abstract<br>
<br>
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margin-left:5.05pt;margin-bottom:.0001pt"><b
style="mso-bidi-font-weight:normal"><span lang="EN-US">CREATING
MICROENVIRONMENTS FOR TISSUE REGENERATION</span></b></p>
<br>
<p class="MsoBodyText"
style="margin-right:38.5pt;line-height:107%"><span lang="EN-US">1Institute
for Bioengineering of Catalonia (IBEC), The Barcelona
Institute of Science and Technology, Barcelona, Spain</span></p>
<p class="MsoBodyText" style="margin-top:7.95pt"><span
lang="EN-US">2CIBER
Bioengineering, Biomaterials and Nanotechnology, Spain</span></p>
<span lang="EN-US">3Dept. Materials Science and Engineering, EEBE,
Technical University
of Catalonia (UPC), Barcelona, Spain<br>
</span><span style="font-size:
13.5pt;mso-bidi-font-size:11.0pt" lang="EN-US"> </span><span
lang="EN-US"><br>
Biomaterials have been used in regenerative medicine for years,
but
they have been mainly used as scaffolds to support and guide
cells or as cell
and signaling delivery carriers. Our research has focused in how
the
biomaterials interact with the host environment. We have
determined that no
biomaterial is inert and that all of them can affect cell
behavior.</span>
<p class="MsoBodyText" style="margin-right:7.1pt;line-height:107%"><span
lang="EN-US">Understanding how cells interact with the
biomaterials and how the
degradation products can activate metabolically the cells
allows the creation
of microenvironments that can induce cell reprograming and
activation of stem
and progenitor cells.</span></p>
<span lang="EN-US">Cells are susceptible to change their phenotype
and function in
response to the designed scaffolds. The selected material,
topography, scaffold
structure and degradation products have to be optimized to
fulfil the
requirements for each tissue (1,2). We have demonstrated that
biomaterials
themselves can activate stem cells at their niche and can either
differentiate
them or dedifferentiate adult cells towards a more precursor
phenotype. This is
perfect for in situ tissue engineering<span
style="letter-spacing:-.25pt"> </span>applications.</span><span
lang="EN-US"><br>
<br>
The way how we can translate and transfer the technology into
products will have a lot to do in how they are fabricated and
how is the
interaction with the cells and tissues.</span><span lang="EN-US"></span>
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<br>
Saludos<br>
Raúl<br>
<br>
<pre class="moz-signature">--
Raúl Mendoza Jiménez
Técnico de Apoyo a la Investigación INA
c/Mariano Esquillor s/n. (50018) zaragoza.
edificio i+d+i. Campus Rio Ebro. Universidad de Zaragoza
INA - Instituto de Nanociencia de Aragón
tel: +34 976 762865. fax: +34 976 762776
web: <a class="moz-txt-link-freetext" href="http://ina.unizar.es">http://ina.unizar.es</a>
e-mail: <a class="moz-txt-link-abbreviated" href="mailto:rmendoza@unizar.es">rmendoza@unizar.es</a>
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