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<p>For info...Hubo una sesión específica de RAP ayer antes del
congreso y fue Helen, nos manda sus notas.</p>
<p>Julia<br>
</p>
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<td>Re: UKB RAP Q&A session</td>
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<th valign="BASELINE" align="RIGHT" nowrap="nowrap">Date: </th>
<td>Tue, 10 Dec 2024 17:28:20 +0100</td>
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<th valign="BASELINE" align="RIGHT" nowrap="nowrap">From: </th>
<td>William Young <a class="moz-txt-link-rfc2396E" href="mailto:w.young@qmul.ac.uk"><w.young@qmul.ac.uk></a></td>
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<td>pbmlab <a class="moz-txt-link-rfc2396E" href="mailto:pbmlab@qmul.ac.uk"><pbmlab@qmul.ac.uk></a></td>
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<th valign="BASELINE" align="RIGHT" nowrap="nowrap">To: </th>
<td>pbmlab <a class="moz-txt-link-rfc2396E" href="mailto:pbmlab@qmul.ac.uk"><pbmlab@qmul.ac.uk></a></td>
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<div dir="auto">Thanks Helen for sharing. </div>
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<div dir="auto">BW</div>
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<div dir="auto">Will</div>
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<div dir="auto"><span
style="font-family:Calibri, Arial, Helvetica, sans-serif;font-size:12pt;margin:0px;line-height:1.5"><span
style="font-size: 11pt; margin: 0px; color: rgb(0, 36, 81);">==========================================</span></span><span
style="font-family:Calibri, Arial, Helvetica, sans-serif;display:inline !important"></span>
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<span
style="font-size: 11pt; margin: 0px; color: rgb(0, 36, 81);"><i>Dr
William J Young MRCP, PhD</i></span></div>
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<span
style="font-size: 11pt; margin: 0px; color: rgb(0, 36, 81);"><i>NIHR
Clinical Lecturer, Queen Mary University of London</i></span></div>
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<span
style="font-size: 11pt; margin: 0px; color: rgb(0, 36, 81);"><i><i
style="background-color: rgb(255, 255, 255);"><i
style="background-color: rgb(255, 255, 255);">Electrophysiology
Cardiology Registrar, Barts Heart Centre</i></i><br>
</i></span></div>
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<div id="divRplyFwdMsg" dir="ltr"><font face="Calibri, sans-serif"
style="font-size:11pt" color="#000000"><b>From:</b>
<a class="moz-txt-link-abbreviated" href="mailto:pbmlab-request@qmul.ac.uk">pbmlab-request@qmul.ac.uk</a> <a class="moz-txt-link-rfc2396E" href="mailto:pbmlab-request@qmul.ac.uk"><pbmlab-request@qmul.ac.uk></a> on
behalf of Helen Warren <a class="moz-txt-link-rfc2396E" href="mailto:h.r.warren@qmul.ac.uk"><h.r.warren@qmul.ac.uk></a><br>
<b>Sent:</b> Tuesday, December 10, 2024 4:16:45 PM<br>
<b>To:</b> pbmlab <a class="moz-txt-link-rfc2396E" href="mailto:pbmlab@qmul.ac.uk"><pbmlab@qmul.ac.uk></a><br>
<b>Subject:</b> UKB RAP Q&A session</font>
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Dear all,</div>
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Sharing here my notes from this morning's pre-conference
session, as I was the only one who attended...</div>
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(Hope my quick notes make some sense to others...)</div>
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Best wishes,</div>
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Helen</div>
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<p
style="margin:0px 0px 3px; font-size:28px; color:rgb(0,0,0)"><span
style="font-family:UICTFontTextStyleBody; font-weight:bold">UKB Dec 2024
Conference<span> </span></span></p>
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<p style="margin:0px; font-size:17px; color:rgb(0,0,0)"><span
style="font-family:UICTFontTextStyleBody; font-weight:normal">## UKB-RAP
Q&A session:</span></p>
<ul style="color:rgb(0,0,0)">
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Mandatory
training!!</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">UKB GitHub has
lots of notebooks with example scripts, which also state
recommended instances, to give you an idea of run-time
& cost etc</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Parallel
computing always better</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Better/cheaper
to use bespoke apps</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Lots of
training & videos available</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">If ever we
need more compute power for large-scale analyses, we can
email the UKB dnanexus support team, and request more,
they’re happy to help<span> </span></span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Recently
published a paper on policy guidance for how best to use
AI on the UKB dataset</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Use UKB
community forum</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">eg Q about
working group for AI & ML methods in UKB</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Data Showcase
can’t be used to cross-reference or cross-tabulate
between different data-fields. For data anonymity. So,
if we have a specific query,<span> </span></span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">One of the
simple examples for running a GWAS, is for height; a
more complex one is for BP! And helps with
categorisation of different sources of different BP data
field measurements<span> </span></span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Simple example
is using PLINK (which is ok for small N datasets)</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Then also a
step-by-step tutorial for running a GWAS using REGENIE
(which is better for large N analyses)</span></li>
<li style="margin:0px; font-weight:normal; font-size:17px"><span
style="font-family:UICTFontTextStyleBody">Q from UKB
team, whether researchers would find it helpful to have
a synthetic dataset to use for tutorials & training
>> I said YES!<span> </span></span></li>
</ul>
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