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<div class="moz-cite-prefix">Thanks Malcolm.</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">Bio-chemistry was launched (say) after
Whöler inorganic synthesis of urea. <br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">Bio-physics was launched after Meyerhof
and Lohmann on ATP phosphate-bond energetics (or more recently,
Morowitz "energy flow in the biosphere")<br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">Bio-information was launched after...
in my opinion after Ulrich and Galperin recent works on
prokaryotic (one-component) signaling systems.<br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">Why? We may finally ascertain the whole
"information flow", that every substance "ingested" is first
"touched" or "tasted" by the OCSs; and we may connect this with
the life cycle advancement, with multicellularity, etc. <br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">So, that's the defined biological
phenomenon. No more secret sauces!<br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">Best--Pedro<br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix"><br>
</div>
<div class="moz-cite-prefix">El 21/01/2022 a las 2:45, Malcolm Dean
escribió:<br>
</div>
<blockquote type="cite"
cite="mid:CAEu1PWBn8GdcM_GaruMrsuE2VKRegT7BzsrurT+P3c_UPvr4sw@mail.gmail.com">
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<div dir="auto">Without a defined phenomenon, there will be little
progress.
<div dir="auto"><br>
</div>
<div dir="auto">Often "Information" is used like a secret sauce.<br>
<br>
<div data-smartmail="gmail_signature" dir="auto">Malcolm</div>
</div>
</div>
<br>
<div class="gmail_quote">
<div dir="ltr" class="gmail_attr">---------- Forwarded message
---------<br>
</div>
Date: Wed, 19 Jan 2022 19:55:48 +0100<br>
From: Pedro C. Mariju?n <<a
href="mailto:pedroc.marijuan@gmail.com" target="_blank"
rel="noreferrer" moz-do-not-send="true">pedroc.marijuan@gmail.com</a>><br>
To: "'fis'" <<a href="mailto:fis@listas.unizar.es"
target="_blank" rel="noreferrer" moz-do-not-send="true">fis@listas.unizar.es</a>><br>
Subject: Re: [Fis] NEW YEAR LECTURE (Youri Timsit)<br>
Message-ID: <<a
href="mailto:8fe0691f-6d5f-7abe-d882-f2c2ed885378@gmail.com"
target="_blank" rel="noreferrer" moz-do-not-send="true">8fe0691f-6d5f-7abe-d882-f2c2ed885378@gmail.com</a>><br>
Content-Type: text/plain; charset="utf-8"; Format="flowed"<br>
<br>
Dear Youri and All,<br>
<br>
Gojng back to the Lecture theme, one of the things that worries
me is <br>
the biological disarray when having to deal with "the
informational." I <br>
mean, when you work with the relational properties of these
fascinating <br>
ribosomal proteins, apart of mathematical-statistical techniques
and <br>
algorithms to make sense of their interactions and evolutionary
<br>
co-adaptations, you have nothing else but to recur to the
metaphor, <br>
"molecular brains", neural like", etc.? It is fine, as you do
not have <br>
any consisting framework to refer to. It already happened to the
<br>
proponents of "bacterial intelligence", also forced to the
metaphor <br>
(Bray, Armitage...).<br>
<br>
In my view, tools from maths, statistics, computer science, etc.
are <br>
just that, tools. Ironically some of these tools themselves had
<br>
biological origins (genetic algorithms, neural networks,
perceptrons). <br>
So, my contention is that a new filed like bio-chemistry or
bio-physics <br>
would be needed concerning the biological-informational themes,
a <br>
bio-information discipline comparable to those just mentioned.
According <br>
to several authors? (me included), the prokaryotic cell should
be <br>
considered as the fundamental, basic unit of biological
cognition. <br>
Thereafter, there would be different ways to characterize its <br>
informational processes, particularly along the "information
flow" <br>
conceptualization... interested parties may go to the recent <br>
contribution of Jorge Navarro and mine: <br>
<a href="https://www.mdpi.com/1422-0067/22/21/11965"
rel="noreferrer noreferrer" target="_blank"
moz-do-not-send="true">https://www.mdpi.com/1422-0067/22/21/11965</a>
, it is in the special issue <br>
coordinated by Youri.? I also discuss that the from the
informational <br>
thinking one could find the ways and means to renew the outdated
Modern <br>
Synthesis.<br>
<br>
Otherwise, without a clearer disciplinary framework, am afraid
the new <br>
biology will be reduced to bioinformatics and experimental
"omic" <br>
disciplines. Just another (advanced, "very advanced")
technology.<br>
<br>
Best wishes to All,<br>
--Pedro<br>
</div>
</blockquote>
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