<html><head><meta http-equiv="Content-Type" content="text/html charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Dear Pedro,<div class=""><br class=""></div><div class=""><br class=""><div><blockquote type="cite" class=""><div class="">On 18 Sep 2020, at 20:01, Pedro C. Marijuan <<a href="mailto:pcmarijuan.iacs@aragon.es" class="">pcmarijuan.iacs@aragon.es</a>> wrote:</div><br class="Apple-interchange-newline"><div class="">
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8" class="">
<div class="">
Dear All,<br class="">
Thanks to Jose Javier for his comments. Regarding the loop you
mention about distinction, you are right, but this is a very
characteristic of life (see that Maturana and Varela already said
something pretty similar in their Tree of Knowledge). In the other
biological principles that follow (below) I try to clarify that
notion in several directions, particularly concerning signaling
systems, a concept which was completely ignored until well in the
1990s. Your second comment may be partially responded looking at
those further principles dealing with the symbolic communication via
language and the social narratives, not far from what you have
pointed. Thus I include the whole principles herein.<br class="">
<!--[if gte mso 9]><xml>
<o:OfficeDocumentSettings>
<o:RelyOnVML/>
<o:AllowPNG/>
</o:OfficeDocumentSettings>
</xml><![endif]--><!--[if gte mso 9]><xml>
<w:WordDocument>
<w:View>Normal</w:View>
<w:Zoom>0</w:Zoom>
<w:TrackMoves/>
<w:TrackFormatting/>
<w:HyphenationZone>21</w:HyphenationZone>
<w:PunctuationKerning/>
<w:ValidateAgainstSchemas/>
<w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid>
<w:IgnoreMixedContent>false</w:IgnoreMixedContent>
<w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText>
<w:DoNotPromoteQF/>
<w:LidThemeOther>ES</w:LidThemeOther>
<w:LidThemeAsian>X-NONE</w:LidThemeAsian>
<w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript>
<w:Compatibility>
<w:BreakWrappedTables/>
<w:SnapToGridInCell/>
<w:WrapTextWithPunct/>
<w:UseAsianBreakRules/>
<w:DontGrowAutofit/>
<w:SplitPgBreakAndParaMark/>
<w:DontVertAlignCellWithSp/>
<w:DontBreakConstrainedForcedTables/>
<w:DontVertAlignInTxbx/>
<w:Word11KerningPairs/>
<w:CachedColBalance/>
</w:Compatibility>
<m:mathPr>
<m:mathFont m:val="Cambria Math"/>
<m:brkBin m:val="before"/>
<m:brkBinSub m:val="--"/>
<m:smallFrac m:val="off"/>
<m:dispDef/>
<m:lMargin m:val="0"/>
<m:rMargin m:val="0"/>
<m:defJc m:val="centerGroup"/>
<m:wrapIndent m:val="1440"/>
<m:intLim m:val="subSup"/>
<m:naryLim m:val="undOvr"/>
</m:mathPr></w:WordDocument>
</xml><![endif]--><!--[if gte mso 9]><xml>
<w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="true"
DefSemiHidden="true" DefQFormat="false" DefPriority="99"
LatentStyleCount="267">
<w:LsdException Locked="false" Priority="0" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Normal"/>
<w:LsdException Locked="false" Priority="9" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="heading 1"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 2"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 3"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 4"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 5"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 6"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 7"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 8"/>
<w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 9"/>
<w:LsdException Locked="false" Priority="39" Name="toc 1"/>
<w:LsdException Locked="false" Priority="39" Name="toc 2"/>
<w:LsdException Locked="false" Priority="39" Name="toc 3"/>
<w:LsdException Locked="false" Priority="39" Name="toc 4"/>
<w:LsdException Locked="false" Priority="39" Name="toc 5"/>
<w:LsdException Locked="false" Priority="39" Name="toc 6"/>
<w:LsdException Locked="false" Priority="39" Name="toc 7"/>
<w:LsdException Locked="false" Priority="39" Name="toc 8"/>
<w:LsdException Locked="false" Priority="39" Name="toc 9"/>
<w:LsdException Locked="false" Priority="35" QFormat="true" Name="caption"/>
<w:LsdException Locked="false" Priority="10" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Title"/>
<w:LsdException Locked="false" Priority="1" Name="Default Paragraph Font"/>
<w:LsdException Locked="false" Priority="11" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Subtitle"/>
<w:LsdException Locked="false" Priority="22" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Strong"/>
<w:LsdException Locked="false" Priority="20" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Emphasis"/>
<w:LsdException Locked="false" Priority="59" SemiHidden="false"
UnhideWhenUsed="false" Name="Table Grid"/>
<w:LsdException Locked="false" UnhideWhenUsed="false" Name="Placeholder Text"/>
<w:LsdException Locked="false" Priority="1" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="No Spacing"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 1"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 1"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 1"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 1"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 1"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 1"/>
<w:LsdException Locked="false" UnhideWhenUsed="false" Name="Revision"/>
<w:LsdException Locked="false" Priority="34" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="List Paragraph"/>
<w:LsdException Locked="false" Priority="29" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Quote"/>
<w:LsdException Locked="false" Priority="30" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Intense Quote"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 1"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 1"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 1"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 1"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 1"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 1"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 1"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 1"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 2"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 2"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 2"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 2"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 2"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 2"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 2"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 2"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 2"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 2"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 2"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 2"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 2"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 2"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 3"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 3"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 3"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 3"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 3"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 3"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 3"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 3"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 3"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 3"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 3"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 3"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 3"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 3"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 4"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 4"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 4"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 4"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 4"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 4"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 4"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 4"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 4"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 4"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 4"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 4"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 4"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 4"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 5"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 5"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 5"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 5"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 5"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 5"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 5"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 5"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 5"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 5"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 5"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 5"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 5"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 5"/>
<w:LsdException Locked="false" Priority="60" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Shading Accent 6"/>
<w:LsdException Locked="false" Priority="61" SemiHidden="false"
UnhideWhenUsed="false" Name="Light List Accent 6"/>
<w:LsdException Locked="false" Priority="62" SemiHidden="false"
UnhideWhenUsed="false" Name="Light Grid Accent 6"/>
<w:LsdException Locked="false" Priority="63" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 1 Accent 6"/>
<w:LsdException Locked="false" Priority="64" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Shading 2 Accent 6"/>
<w:LsdException Locked="false" Priority="65" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 1 Accent 6"/>
<w:LsdException Locked="false" Priority="66" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium List 2 Accent 6"/>
<w:LsdException Locked="false" Priority="67" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 1 Accent 6"/>
<w:LsdException Locked="false" Priority="68" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 2 Accent 6"/>
<w:LsdException Locked="false" Priority="69" SemiHidden="false"
UnhideWhenUsed="false" Name="Medium Grid 3 Accent 6"/>
<w:LsdException Locked="false" Priority="70" SemiHidden="false"
UnhideWhenUsed="false" Name="Dark List Accent 6"/>
<w:LsdException Locked="false" Priority="71" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Shading Accent 6"/>
<w:LsdException Locked="false" Priority="72" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful List Accent 6"/>
<w:LsdException Locked="false" Priority="73" SemiHidden="false"
UnhideWhenUsed="false" Name="Colorful Grid Accent 6"/>
<w:LsdException Locked="false" Priority="19" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis"/>
<w:LsdException Locked="false" Priority="21" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Intense Emphasis"/>
<w:LsdException Locked="false" Priority="31" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Subtle Reference"/>
<w:LsdException Locked="false" Priority="32" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Intense Reference"/>
<w:LsdException Locked="false" Priority="33" SemiHidden="false"
UnhideWhenUsed="false" QFormat="true" Name="Book Title"/>
<w:LsdException Locked="false" Priority="37" Name="Bibliography"/>
<w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading"/>
</w:LatentStyles>
</xml><![endif]--><!--[if gte mso 10]>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:"Tabla normal";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-qformat:yes;
mso-style-parent:"";
mso-padding-alt:0cm 5.4pt 0cm 5.4pt;
mso-para-margin:0cm;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:11.0pt;
font-family:"Calibri","sans-serif";
mso-ascii-font-family:Calibri;
mso-ascii-theme-font:minor-latin;
mso-fareast-font-family:"Times New Roman";
mso-fareast-theme-font:minor-fareast;
mso-hansi-font-family:Calibri;
mso-hansi-theme-font:minor-latin;
mso-bidi-font-family:"Times New Roman";
mso-bidi-theme-font:minor-bidi;}
</style>
<![endif]--><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">1. Information is
distinction on an <i style="mso-bidi-font-style:normal" class="">adjacent
</i>difference. <span style="color:red" class=""></span></span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">2. Information processes
consist in organized action upon differences collected onto
structures, patterns, sequences, messages, or flows.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">3. Information flows are
essential organizers of life's self-production process –the life
cycle– anticipating, shaping, and mixing up with the
accompanying energy flows.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">4. Proto-phenomena of
meaning, knowledge, and cognition (& intelligence) emerge
via signaling systems of living cells, fully developed in the
action/perception cycle of central nervous systems.</span></p><div class=""><br class=""></div></div></div></blockquote><div><br class=""></div><div>That needs some strong infinity axioms in the ontology, incompatible with the idea that a brain is Turing emulable.</div><div><br class=""></div><div>Fundamentally, the matter which made the lining cells originated in the information treatment already emulated by the universal number relation in arithmetic.</div><div><br class=""></div><div>Many things here works for the human sort of information, but to make information relying on some primitive matter prevent the natural solution of the mind-body problem that the universal machine or number already provide.</div><div><br class=""></div><div>To make that matter playing some role here can lead to a reductionist conception of number and machine already refuted by the incompleteness phenomenon.</div><div><br class=""></div><div>In arithmetic, things go in this way: Numbers => universal numbers => differentiating consciousness fluxes => emergences of the first person plural physical reality => emergence of human => human consciousness.</div><div><br class=""></div><div>Digital Mechanism in the cognitive science extends Darwin up to the very origin of the physical laws, from the immaterial information treatment brought by the Turing universal relation among natural numbers.</div><div><br class=""></div><div>This remark is concerned only with the fundamental question, and might be not of interest for the problem of applied human information theory, though.</div><div><br class=""></div><div><br class=""></div><div><br class=""></div><div><br class=""></div><br class=""><blockquote type="cite" class=""><div class=""><div class=""><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">5.
Information/communication exchanges among adaptive life-cycles
underlie the complexity of biological organization at all
scales.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">6. It is symbolic language
what conveys the essential communication exchanges of
individuals —and constitutes the core of human "social nature."</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">7. Human information can
be transformed into efficient knowledge by following the
"knowledge instinct", further enhanced and delimited by
collectively applying rigorous methodologies.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">8. Human cognitive
limitations are partially overcome via "knowledge ecologies",
where knowledge circulates and recombines socially in a
continuous actualization that involves "creative destruction" of
theories, practices, and disciplines.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">9. Narratives become
encapsulated forms of “natural intelligence”, tailored to
capture collective attention and memory, and essential for the
cohesion of social, political, and economic structures.</span></p><p class="MsoNormal" style="margin-bottom:0cm;margin-bottom:.0001pt;text-align:
justify;line-height:14.0pt;mso-line-height-rule:exactly;tab-stops:382.75pt"><span style="font-size: 12pt;" lang="EN-US" class="">10. Information science
proposes a new, radical vision on how information and knowledge
surround individual lives, with profound consequences for
scientific-philosophical practice and for social governance.</span></p>
<br class=""><p class="">Briefly referring to the other discussion track (Christophe), I
quite agree with situating the origins of (genuine) meaning with
living beings, but have some trouble with "constraints" when
generally applied to biological cognition. I think they may be
more useful in other fields (originated in kinematics, they become
more and more volatile as used in Dynamic Systems Theory, and
similarly weakened when going from AI to biological cognition).
For instance, given 3,000 genes in Ecoli, organized in mixed
clusters of fiendish complexity, how do you establish meaningful
constraints? Or can even attribute separate "functions"? You may
see in DOI:<a class=" nova-e-link--color-inherit
nova-e-link nova-e-link--theme-decorated" href="https://www.researchgate.net/deref/http%3A%2F%2Fdx.doi.org%2F10.1016%2Fj.pbiomolbio.2015.07.002?_sg%5B0%5D=nH-ziIzFNlPKAqMszwKA9aJSdUF_He_Rfcal3jUKXaF_lvDrbTWXcTEDtf5uNRaHZMzJ0MFczgM3J-aub54-p6oiQA.Vi1baoaYqIl4vlby-pQVd58ob8urom6m0dhZo1yJ26_NjwihWirad9bxSivcVUymzy-vS1FcL9dD4ZQ7UDtz_w">
10.1016/j.pbiomolbio.2015.07.002</a><span class=" nova-e-link--color-inherit nova-e-link--theme-decorated nova-e-link
"> </span><span class=" nova-e-link--color-inherit
nova-e-link nova-e-link--theme-decorated">the very dimensions of this
ontology problem.</span><a class=" nova-e-link--color-inherit nova-e-link--theme-decorated nova-e-link
" href="https://www.researchgate.net/deref/http%3A%2F%2Fdx.doi.org%2F10.1016%2Fj.pbiomolbio.2015.07.002?_sg%5B0%5D=nH-ziIzFNlPKAqMszwKA9aJSdUF_He_Rfcal3jUKXaF_lvDrbTWXcTEDtf5uNRaHZMzJ0MFczgM3J-aub54-p6oiQA.Vi1baoaYqIl4vlby-pQVd58ob8urom6m0dhZo1yJ26_NjwihWirad9bxSivcVUymzy-vS1FcL9dD4ZQ7UDtz_w"><br class="">
</a></p><p class="">Regarding Marcus' comment on life as imprecisely defined (and
whether viruses or Gaia are 'alive'), the fundamental issue in
natural sciences is "explaining" rather than defining. And
fortunately the advancement in our explanations of life in last
decades has been fantastic. Life can now be characterized in every
basic aspect with amazing depth. One cannot give a precise
definition of life, but one can provide a list of essential
characteristics, and at the center are the informational ones.
Empirically, the point is that information appears to be so
ingrained in the molecular organization of life that scores of new
bio-disciplines have been recently launched around it:
bioinformatics, bioinformation, biocomputation, all the "omic"
fields, signaling science, etc. Biosemiotics could be included
too, but Hélas, most biosemioticians continue to "read" the DNA
meaning via the genetic code, rather than exploring the "signals"
abduced from the environment and "distinctionally worked out and
transcribed in genes--from which ultimately "meaning" emerges.
</p></div></div></blockquote><div>Just to be sure, I agree with this, but eventually Nature itself is a pattern emerging from the relation between universal numbers; some playing the role of environment for others.</div><div><br class=""></div><div><br class=""></div><br class=""><blockquote type="cite" class=""><div class=""><div class=""><p class="">About viruses concretely, they have been essential in the origins
of eukaryotic complexity and in the dynamic balance of marine and
terrestrial ecosystems... irrespective on how we consider their
degree of "aliveness". And finally "non comment" about some
(baiting?) expressions in your previous reply. <br class=""></p></div></div></blockquote><div>The problem of defining consciousness is real (and solved in the Mechanist frame). I don’t see any such problem with life, where the boundaries are just a bit arbitrary. Is a cigarette box alive? It has a complex reproduction cycle, involving actions on the human brain, so why not?</div><div><br class=""></div><div>The question of consciousness is more difficult. Eventually its Mechanist solution forces to abandon Aristotle Metaphysics (the existence of a physical universe “out there” for a more Pytahgorean or Platonic (numbers or ideas) ontology.</div><div><br class=""></div><div>Best,</div><div><br class=""></div><div>Bruno</div><div><br class=""></div><div><br class=""></div><br class=""><blockquote type="cite" class=""><div class=""><div class=""><p class="">
</p><p class="">I see right now the careful "review" by Loet: better for a next
occasion!<br class="">
</p><p class="">Best--Pedro</p><p class="">PS. The Three Messages per Week are counted following the
international business week (from Monday to Sunday included).<br class="">
</p>
<pre class="moz-signature" cols="72">--
-------------------------------------------------
Pedro C. Marijuán
Grupo de Bioinformación / Bioinformation Group
<a class="moz-txt-link-abbreviated" href="mailto:pcmarijuan.iacs@aragon.es">pcmarijuan.iacs@aragon.es</a>
<a class="moz-txt-link-freetext" href="http://sites.google.com/site/pedrocmarijuan/">http://sites.google.com/site/pedrocmarijuan/</a>
------------------------------------------------- </pre>
<div id="DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2" class=""><br class=""> <table style="border-top: 1px solid #D3D4DE;" class="">
<tbody class=""><tr class="">
<td style="width: 55px; padding-top: 18px;" class=""><a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient" target="_blank" class=""><img src="https://ipmcdn.avast.com/images/icons/icon-envelope-tick-round-orange-animated-no-repeat-v1.gif" alt="" width="46" height="29" style="width: 46px; height: 29px;" class=""></a></td>
<td style="width: 470px; padding-top: 17px; color: #41424e; font-size: 13px; font-family: Arial, Helvetica, sans-serif; line-height: 18px;" class="">Libre de virus. <a href="https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=emailclient" target="_blank" style="color: #4453ea;" class="">www.avast.com</a> </td>
</tr>
</tbody></table>
<a href="x-msg://155/#DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2" width="1" height="1" class=""> </a></div></div>
_______________________________________________<br class="">Fis mailing list<br class=""><a href="mailto:Fis@listas.unizar.es" class="">Fis@listas.unizar.es</a><br class="">http://listas.unizar.es/cgi-bin/mailman/listinfo/fis<br class="">----------<br class="">INFORMACI�N SOBRE PROTECCI�N DE DATOS DE CAR�CTER PERSONAL<br class=""><br class="">Ud. recibe este correo por pertenecer a una lista de correo gestionada por la Universidad de Zaragoza.<br class="">Puede encontrar toda la informaci�n sobre como tratamos sus datos en el siguiente enlace: https://sicuz.unizar.es/informacion-sobre-proteccion-de-datos-de-caracter-personal-en-listas<br class="">Recuerde que si est� suscrito a una lista voluntaria Ud. puede darse de baja desde la propia aplicaci�n en el momento en que lo desee.<br class="">http://listas.unizar.es<br class="">----------<br class=""></div></blockquote></div><br class=""></div></body></html>