<div>Dear FISers, </div><div><br></div><div>it's excruciating...</div><div>We did not even find an unique definition of information, life, brain activity, consciousness...</div><div>How could the science improve, if it lacks definitions of what itself is talking about?</div><div><br></div><div>It seems that we depicted a rather dark, hopeless picture... However, there is, I thing, a light in front of us. </div><div>I think that the best way to proceed, at least the most useful in the last centuries, is the one pursued by Einstein: to build an abstract, rather geometric , mathematical model, make testable previsions and then to check if it works in the real world.</div><div>Therefore, I think, we need novel, fresh models and theories, more than experiments aiming to demonstrate theory-laden, pre-cooked, previsions of scientists. </div><div>It is the old problem of science: from above, or from below? Which is the best approach? </div><div>The knowledge of the most elementary biological and physical issues is so scarce, as demonstrated by this FIS discussion involving foremost scientists from all over the world, that the right approach, I think, is to start from above... </div><div>from topology, of course.... </div><div><br></div><div><br><br><p class="MsoNormalCxSpFirst" style="margin-top:12.0pt;margin-right:0cm;
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line-height:115%;mso-layout-grid-align:none;text-autospace:none"><span style="font-size: 14px; line-height: normal; text-align: start;"><font face="courier new, monospace"><b>Arturo Tozzi</b></font></span></p><p class="MsoNormalCxSpFirst" style="margin-top:12.0pt;margin-right:0cm;
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line-height:115%;mso-layout-grid-align:none;text-autospace:none"><span style="line-height: 115%;"><font face="courier new, monospace">AA Professor Physics, University North Texas</font></span></p><p class="MsoNormalCxSpFirst" style="margin-top:12.0pt;margin-right:0cm;
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line-height:115%;mso-layout-grid-align:none;text-autospace:none"><span style="font-size: 14px; line-height: normal; text-align: start;"><font face="courier new, monospace">Pediatrician ASL Na2Nord, Italy</font></span></p><p class="MsoNormalCxSpFirst" style="margin-top:12.0pt;margin-right:0cm;
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line-height:115%;mso-layout-grid-align:none;text-autospace:none"><span style="font-size: 14px; line-height: normal; text-align: start;"><font face="courier new, monospace">Comput Intell Lab, University Manitoba</font></span></p><p class="MsoNormalCxSpFirst" style="margin-top:12.0pt;margin-right:0cm;
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line-height:115%;mso-layout-grid-align:none;text-autospace:none"><font face="courier new, monospace"><a href="http://arturotozzi.webnode.it/" style="font-size: 14px; color: rgb(5, 68, 126); line-height: normal; text-align: start;">http://arturotozzi.webnode.it/</a><span style="font-size: 14px; line-height: normal; text-align: start;"> </span></font><br></p></div><br>