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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Dear Steven and colleagues, <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>I did not (yet) study your approach. Is there a paper that can be read as an introduction?<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>It seems to me that one can distinguish between formal and substantial theories of information. Shannon’s mathematical theory is a formal apparatus: the design and the results do not yet have meaning without an interpretation in a substantial context. On the other side, a theory about, for example, neuro-information is a special theory. One can in this context use information theory as a statistical tool (among other tools). Sometimes, one can move beyond description. </span><span style='font-size:11.0pt;font-family:Wingdings;color:#1F497D'>J</span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>The advantage of information theory, from this perspective of special theories, is that the formal apparatus allows us sometimes to move between domains heuristically. For example, a model of the brain can perhaps be used metaphorically for culture or the economy (or vice versa). The advantages have to be shown in empirical research: which questions can be addressed and which puzzles be solved?<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Best,<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Loet<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div class=MsoNormal align=center style='text-align:center'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><hr size=3 width="100%" align=center></span></div><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Loet Leydesdorff <o:p></o:p></span></p><p class=MsoNormal><i><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Emeritus</span></i><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> University of Amsterdam<br>Amsterdam School of Communications Research (ASCoR)<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="mailto:loet@leydesdorff.net" title="mailto:loet@leydesdorff.net"><span style='font-size:10.0pt'>loet@leydesdorff.net </span></a></span><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>; </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.leydesdorff.net/" title="http://www.leydesdorff.net/"><span style='font-size:10.0pt'>http://www.leydesdorff.net/</span></a></span><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> <br></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Honorary Professor, </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.sussex.ac.uk/spru/"><span style='font-size:9.0pt'>SPRU, </span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>University of Sussex; <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Guest Professor </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.zju.edu.cn/english/"><span style='font-size:9.0pt'>Zhejiang Univ.</span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>, Hangzhou; Visiting Professor, </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.istic.ac.cn/Eng/brief_en.html"><span style='font-size:9.0pt'>ISTIC, </span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Beijing;<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Visiting Professor, </span><a name="_GoBack"></a><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.bbk.ac.uk/"><span style='font-size:9.0pt'>Birkbeck</span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>, University of London; <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://scholar.google.com/citations?user=ych9gNYAAAAJ&hl=en"><span style='font-size:9.0pt'>http://scholar.google.com/citations?user=ych9gNYAAAAJ&hl=en</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>From:</span></b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> stevenzenith@gmail.com [mailto:stevenzenith@gmail.com] <b>On Behalf Of </b>Steven Ericsson-Zenith<br><b>Sent:</b> Tuesday, December 09, 2014 10:13 PM<br><b>To:</b> loet@leydesdorff.net<br><b>Cc:</b> Joseph Brenner; fis<br><b>Subject:</b> Re: [Fis] Information-as-Process<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><div><p class=MsoNormal><span style='font-size:10.0pt'>The problem with this approach (and approaches like it) is that it is descriptive and not explanatory. The distribution of the shape, in my model, can be described, perhaps, but the process or action decision point and response covariance is impossible to consider. </span><o:p></o:p></p><div><p class=MsoNormal><span style='font-size:10.0pt'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.0pt'>It is for this reason that I use holomorphic functors and hyper-functors in which I can express the explicit role of a base universal (per gravitation).<o:p></o:p></span></p><div><p class=MsoNormal><span style='font-size:10.0pt'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-size:10.0pt'>Nor is it clear to me that this is what Joe referred to as "information as process."<o:p></o:p></span></p></div></div></div><div><p class=MsoNormal><o:p> </o:p></p><div><p class=MsoNormal>On Mon, Dec 8, 2014 at 10:20 PM, Loet Leydesdorff <<a href="mailto:loet@leydesdorff.net" target="_blank">loet@leydesdorff.net</a>> wrote:<o:p></o:p></p><blockquote style='border:none;border-left:solid #CCCCCC 1.0pt;padding:0in 0in 0in 6.0pt;margin-left:4.8pt;margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'><div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Dear colleagues, </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Shannon’s information theory can be considered as a calculus because it allows for the dynamic extension. Theil (1972)—Statistical decomposition analysis (North Holland)—distinguished between static and dynamic information measures. In addition to Shannon’s statical H, one can write: </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><img border=0 width=166 height=31 id="Picture_x0020_1" src="cid:image001.png@01D0144D.7CCCAC90" alt="cid:image001.png@01D0144D.7CCCAC90"><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>in which </span><img border=0 width=47 height=27 id="Picture_x0020_2" src="cid:image002.png@01D0144D.7CCCAC90" alt="cid:image002.png@01D0144D.7CCCAC90"><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>can be considered as the a posteriori and </span><img border=0 width=47 height=27 id="Picture_x0020_3" src="cid:image003.png@01D0144D.7CCCAC90" alt="cid:image003.png@01D0144D.7CCCAC90"><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>the a priori distribution. This dynamic information measure can be decomposed and aggregated. One can also develop measures for systemic developments and critical transitions. In other words, information as a process can also be measured in bits of information. Of course, one can extend the dimensionality (<i>i</i>) for the multivariate case (<i>ijk</i>…), and thus use information theory for network analysis (including time).</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Best,</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Loet</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>References:</span><o:p></o:p></p><p style='margin-left:.25in'><a name="14a2db489ee6e0c6__ENREF_1"><span style='font-size:11.0pt;font-family:Symbol;color:#1F497D'>·</span></a><span style='font-size:7.0pt;color:#1F497D'> </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Leydesdorff, L. (1991). The Static and Dynamic Analysis of Network Data Using Information Theory. <i>Social Networks, 13</i>(4), 301-345. </span><o:p></o:p></p><p style='margin-left:.25in'><a name="14a2db489ee6e0c6__ENREF_3"><span style='font-size:11.0pt;font-family:Symbol;color:#1F497D'>·</span></a><span style='font-size:7.0pt;color:#1F497D'> </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Theil, H. (1972). <i>Statistical Decomposition Analysis</i>. Amsterdam/ London: North-Holland.</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal align=center style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:center'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><div class=MsoNormal align=center style='text-align:center'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><hr size=3 width="100%" align=center></span></div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Loet Leydesdorff </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><i><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Emeritus</span></i><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> University of Amsterdam<br>Amsterdam School of Communications Research (ASCoR)</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="mailto:loet@leydesdorff.net" target="_blank" title="mailto:loet@leydesdorff.net"><span style='font-size:10.0pt'>loet@leydesdorff.net </span></a></span><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>; </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.leydesdorff.net/" target="_blank" title="http://www.leydesdorff.net/"><span style='font-size:10.0pt'>http://www.leydesdorff.net/</span></a></span><span style='font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> <br></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Honorary Professor, </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.sussex.ac.uk/spru/" target="_blank"><span style='font-size:9.0pt'>SPRU, </span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>University of Sussex; </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Guest Professor </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.zju.edu.cn/english/" target="_blank"><span style='font-size:9.0pt'>Zhejiang Univ.</span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>, Hangzhou; Visiting Professor, </span><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.istic.ac.cn/Eng/brief_en.html" target="_blank"><span style='font-size:9.0pt'>ISTIC, </span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Beijing;</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>Visiting Professor, </span><a name="14a2db489ee6e0c6__GoBack"></a><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://www.bbk.ac.uk/" target="_blank"><span style='font-size:9.0pt'>Birkbeck</span></a></span><span style='font-size:9.0pt;font-family:"Calibri","sans-serif";color:black'>, University of London; </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><a href="http://scholar.google.com/citations?user=ych9gNYAAAAJ&hl=en" target="_blank"><span style='font-size:9.0pt'>http://scholar.google.com/citations?user=ych9gNYAAAAJ&hl=en</span></a></span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'> </span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'>From:</span></b><span style='font-size:11.0pt;font-family:"Calibri","sans-serif"'> Fis [mailto:<a href="mailto:fis-bounces@listas.unizar.es" target="_blank">fis-bounces@listas.unizar.es</a>] <b>On Behalf Of </b>Steven Ericsson-Zenith<br><b>Sent:</b> Monday, December 08, 2014 10:22 PM<br><b>To:</b> Joseph Brenner<br><b>Cc:</b> fis<br><b>Subject:</b> Re: [Fis] Information-as-Process</span><o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>I am a little mystified by your assertion of "information as process." What, exactly, is this and how does it differ fro information in general (Shannon). Is it related to Whitehead's process notions?<o:p></o:p></p><div><div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>In terms of neuroscience it is important to move away from connectionism and modern computational ideas I believe. It is not clear to me how information theory can be applied to the operation of the brain at the synaptic level because the actions and the decisions made are made across the structure and not at a single location. <o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>Recognition, for example, is not a point event but occurs rather when a particular shape is formed in the structure (of the CNS, for example) and is immediately covariant with the "appropriate" response (another shape) which may be characterized as a hyper-functor (which may or may not include neurons and astrocytes in the brain).<o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>Regards,<o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>Steven<o:p></o:p></p><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div></div></div></div></div><div><div><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p><div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>On Fri, Dec 5, 2014 at 4:39 AM, Joseph Brenner <<a href="mailto:joe.brenner@bluewin.ch" target="_blank">joe.brenner@bluewin.ch</a>> wrote:<o:p></o:p></p><blockquote style='border:none;border-left:solid #CCCCCC 1.0pt;padding:0in 0in 0in 6.0pt;margin-left:4.8pt;margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'>Dear Carolina, Bob L., Bob U., Sören and Krassimir,<br><br>First of all thanks to Carolina for having launched a most interesting thread, of which I have changed the title since the issues are broader than that of Neuroinformation alone, as Francesco has noted.<br><br>My first point is a response to Sören since I feel his book does not address Information-as-Process as 'physically' as I think necessary. His reference to the use of this term by Buckland (on p. 77 not 87), (which I had missed when first reading /Cybersemiotics/), however, is followed by a reference to information processing. (He later states that a new metatheory is required to replace the information processing paradigm, and he proposes Peircean semiotics, whereas I have proposed Logic in Reality.) I also note that Buckland places Information-as-Process in the 'Intangible' column of his matrix and one can question the ontological meaning of this.<br><br>In the compendium /Philosophers of Process/. 1998. Browning and Myers (eds.). New York: Fordham University Press, Peirce is represented by four papers: "The Architecture of Theories", "The Doctrine of Necessity Examined", "The Law of Mind" and "Man's Glassy Essence". Unfortunately, in none of these is the word 'process' used, let alone described as a concept. 'Process' is not an entry in the COMMENS Digital Companion to C. S. Peirce, edited by Bergman and Paavola, so the most one can say is that process was not a common concept in Peirce. If Information-as-Process is to be developed as a concept, I doubt that Peirce's semiotics will help.<br><br>In the notes of both Bob. L and Bob U., however, one finds workable properties than can be assigned to Information-as-Process, the verb-noun dialectic and the concept of real trophic exchange. Krassimir's concept of information being dynamic (a process) or static depending on what it reflects does not give as complete a notion as I would like that information is /in-itself/ a process, even it reflects (refers to) static or abstract objects. Nevertheless, Krassimir clearly sees the dualism of information as composed of dynamic and static entities, whose interaction, as in the case of the first two approaches, can be discussed in the framework of Logic in Reality. The problem is his use of the term 'reflection' whose nature is not clear as I have remarked to him before.<br><br>I look forward to further discussion.<br><br>Best wishes,<br><br>Joseph<br><br><br><br><br>----- Original Message ----- From: "Robert E. Ulanowicz" <<a href="mailto:ulan@umces.edu" target="_blank">ulan@umces.edu</a>><br>To: "Carolina Isiegas" <<a href="mailto:cisiegas@gmail.com" target="_blank">cisiegas@gmail.com</a>><br>Cc: <<a href="mailto:fis@listas.unizar.es" target="_blank">fis@listas.unizar.es</a>><br>Sent: Wednesday, December 03, 2014 6:30 PM<br>Subject: Re: [Fis] Neuroinformation?<br><br><br>Dear Dr. Isiegas:<br><br>I envision neuroinformation as the mutual information of the neuronal<br>network where synaptic connections are weighted by the frequencies of<br>discharge between all pairs of neurons. This is directly analogous to a<br>network of trophic exchanges among an ecosystem, as illustrated in<br><<a href="http://people.biology.ufl.edu/ulan/pubs/SymmOvhd.PDF" target="_blank">http://people.biology.ufl.edu/ulan/pubs/SymmOvhd.PDF</a>>.<br><br>Please note that this measure is different from the conventional<br>sender-channel-receiver format of communications theory. It resembles more<br>the "structural information" inhering in the neuronal network. John<br>Collier (also a FISer) calls such information "enformation" to draw<br>attention to its different nature.<br><br>With best wishes for success,<br><br>Bob Ulanowicz<o:p></o:p></p><blockquote style='border:none;border-left:solid #CCCCCC 1.0pt;padding:0in 0in 0in 6.0pt;margin-left:4.8pt;margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'><p class=MsoNormal style='mso-margin-top-alt:auto;margin-bottom:12.0pt'>Dear list,<br><br> I have been reading during the last year all these interesting<br>exchanges. Some of them terrific discussions! Given my scientific<br>backgound<br>(Molecular Neuroscience), I would like to hear your point of view on the<br>topic of neuroinformation, how information "exists" within the Central<br>Nervous Systems. My task was experimental; I was interested in<br>investigating the molecular mechanisms underlying learning and memory,<br>specifically, the role of the cAMP-PKA-CREB signaling pathway in such<br>brain<br>functions (In Ted Abel´s Lab at the University of Pennsylvania, where I<br>spent 7 years). I generated several genetically modified mice in which I<br>could regulate the expression of this pathway in specific brain regions<br>and<br>in which I studied the effects of upregulation or downregulation at the<br>synaptic and behavioral levels. However, I am conscious that the<br>"information flow" within the mouse Nervous System is far more complex<br>that<br>in the "simple" pathway that I was studying...so, my concrete question for<br>you "Fishers" or "Fisers", how should we contemplate the micro and macro<br>structures of information within the neural realm? what is<br>Neuroinformation?<br><br>Best wishes,<br><br><br>--<br>Carolina Isiegas<br>_______________________________________________<br>Fis mailing list<br><a href="mailto:Fis@listas.unizar.es" target="_blank">Fis@listas.unizar.es</a><br><a href="http://listas.unizar.es/cgi-bin/mailman/listinfo/fis" target="_blank">http://listas.unizar.es/cgi-bin/mailman/listinfo/fis</a><o:p></o:p></p></blockquote><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><br><br>_______________________________________________<br>Fis mailing list<br><a href="mailto:Fis@listas.unizar.es" target="_blank">Fis@listas.unizar.es</a><br><a href="http://listas.unizar.es/cgi-bin/mailman/listinfo/fis" target="_blank">http://listas.unizar.es/cgi-bin/mailman/listinfo/fis</a> <br>_______________________________________________<br>Fis mailing list<br><a href="mailto:Fis@listas.unizar.es" target="_blank">Fis@listas.unizar.es</a><br><a href="http://listas.unizar.es/cgi-bin/mailman/listinfo/fis" target="_blank">http://listas.unizar.es/cgi-bin/mailman/listinfo/fis</a><o:p></o:p></p></blockquote></div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'> <o:p></o:p></p></div></div></div></div></div></blockquote></div><p class=MsoNormal><o:p> </o:p></p></div></div></body></html>